Perianal Crohn Disease

Risk of Repeat Surgery for Perianal Crohn Disease

Perianal involvement of Crohn disease (CD) is known to be a common complication of CD. Due to the wide variety of anal manifestations of CD, the exact prevalence of perianal Crohn disease (PCD) is not known. However, it is estimated that a majority of patients with CD may undergo surgical treatment for PCD. The most common causes of operative treatment are perianal abscesses and anal fistulas b...

Treatment of complex perianal fistulas in Crohn disease: infliximab, surgery or combined approach.

BACKGROUND The aim of this study was to compare the outcomes of the management of perianal fistulas in Crohn disease between infliximab, surgery or a combination of surgery and infliximab. METHODS We prospectively subdivided 35 consecutive patients with Crohn disease with complex perianal fistulas into 3 groups: 11 patients received infliximab (5 mg/kg intravenously at 0, 2 and 6 wk; group A)...

Diagnosis and treatment of perianal Crohn disease: NASPGHAN clinical report and consensus statement.

Inflammatory bowel disease is a chronic inflammatory disorder of the gastrointestinal tract that includes both Crohn disease (CD) and ulcerative colitis. Abdominal pain, rectal bleeding, diarrhea, and weight loss characterize both CD and ulcerative colitis. The incidence of IBD in the United States is 70 to 150 cases per 100,000 individuals and, as with other autoimmune diseases, is on the rise...

Transperineal ultrasonography for evaluation of the perianal fistula and abscess in pediatric Crohn disease: preliminary study

PURPOSE To assess the feasibility and effectiveness of transperineal ultrasonography (TPUS) for the evaluation of perianal Crohn disease (PCD) in pediatric patients. METHODS Between September 2010 and August 2013, 64 TPUS examinations were performed in 43 patients (34 males and 9 females; mean age±standard deviation, 13.3±2.4 years; age range, 6 to 17 years) to evaluate PCD. The pain severity...

Perianal Crohn Disease after Treatment with Rituximab for Active Granulomatosis with Polyangiitis.